KEGG   REACTION: R00036
Entry
R00036                      Reaction                               
Name
5-aminolevulinate hydro-lyase (adding 5-aminolevulinate and cyclizing; porphobilinogen-forming)
Definition
2 5-Aminolevulinate <=> Porphobilinogen + 2 H2O
Equation
2 C00430 <=> C00931 + 2 C00001
Reaction class
RC00918  C00430_C00931
RC01781  C00430_C00931
Enzyme
4.2.1.24
Pathway
rn00860  Porphyrin metabolism
rn01100  Metabolic pathways
rn01110  Biosynthesis of secondary metabolites
rn01120  Microbial metabolism in diverse environments
rn01240  Biosynthesis of cofactors
Module
M00121  Heme biosynthesis, plants and bacteria, glutamate => heme
M00846  Siroheme biosynthesis, glutamyl-tRNA => siroheme
M00868  Heme biosynthesis, animals and fungi, glycine => heme
M00926  Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
Enzymatic reactions [BR:br08201]
 4. Lyase reactions
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.24
     R00036  2 5-Aminolevulinate <=> Porphobilinogen + 2 H2O
Orthology
K01698  porphobilinogen synthase [EC:4.2.1.24]
Other DBs
RHEA: 24067

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (14)   
   KEGG PATHWAY (10)   
   KEGG MODULE (4)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG RCLASS (2)   
Gene (8585)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (8584)   
All databases (8606)   

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